About PENN MRI
Custom Organic Synthesis for your research needs
USA-based lab delivering high-purity compounds with fast, direct collaboration
In Business Since 2008 with Proven Experience
Custom Research & Development
- Designed and executed target-oriented synthesis programs with iterative planning and experimentation
- Delivered research reports, detailed procedures, and high-purity compounds
- Developed routes for natural products suitable for customer manufacturing environments
- Produced pesticide derivatives (gram scale) for metabolite standards
- Conducted literature surveys to identify optimal reaction conditions and synthetic pathways
- Prioritized green chemistry and manufacturing compatibility
- Maintained ongoing client communication with progress updates and strategic recommendations
- Delivered multi-step syntheses at >98% purity (NMR, GC-MS, HPLC)
Custom Synthesis & Scale-Up
- Scaled reactions from lab procedures to 200 g – 1 kg batches
- Performed reaction development and optimization (solvent, concentration, temperature, purification)
- Executed advanced techniques including:
- High vacuum distillation
- Moisture-sensitive recrystallization
- Column chromatography
- Cryogenic reactions
- Developed manufacturing procedures and Master Production Records
- Established QC protocols and specifications (NMR, GC-MS, LC-MS, HPLC, UV-Vis)
- Implemented DOT-compliant shipping and packaging
- Coordinated waste handling and regulatory compliance
RESEARCH COLLABORATION & INNOVATION
Academic and Institutional Collaborations
- Developed computational docking models for small molecule–protein interactions; contributed to peer-reviewed publications and competitive grant proposals.
- Investigated binding modes of natural product inhibitors and supported structure–activity relationship (SAR) studies; collaborated on federally funded research proposals and publications.
Drug Delivery and Biorthogonal Chemistry
- Co-inventor on multiple international patents related to biorthogonal drug delivery systems and implantable materials.
Independent Research Initiatives
- Developed chemically modified biomolecule platforms for immunological applications; contributed to small business innovation grant submissions.
- Developed a pesticide on-demand controlled release system
Why Work With Us
Deep Technical Expertise
PhD-level training with extensive experience in multi-step synthesis, process development, and scale-up.
End-to-End Capability
From route design and feasibility to manufacturing-ready procedures and delivery.
Clear Communication
Regular updates, transparent timelines, and detailed documentation.
Reliable Delivery
Consistent production of high-purity materials with reproducible methods.
Our Process
- Initial Consultation Share your target molecule or project scope
- Feasibility Assessment Route evaluation, risks, and timelines
- Proposal & Quote Defined scope, deliverables, and pricing
- Synthesis & Optimization Execution with ongoing communication
- Delivery & Documentation Final compound with full analytical data and procedures
Applications
- Drug discovery and medicinal chemistry
- Chemical biology
- Agrochemical and metabolite studies
- Materials science
- Academic and translational research
Let’s Solve Your Synthesis Challenge
Complex chemistry doesn’t need to slow your project down. With the right expertise and a focused approach, we can help you get the compounds you need—efficiently, reliably, and at the quality your work demands.
Get Started
Have a project in mind?
We offer a free initial consultation and rapid feasibility feedback.
Contact us today to discuss your synthesis needs.
Our Mission
Chemistry at the Core
Chemistry at the Core
Chemistry is a powerful driver of innovation. We bring technical expertise, creativity, and precision to every custom synthesis project, delivering high-quality solutions while prioritizing sustainability and responsible practices.
Chemistry at the Core
Chemistry at the Core
Chemistry at the Core
Rooted in Organic Chemistry
We are rooted in organic chemistry, with the expertise and practical insight to bring molecular innovations to life through custom synthesis.
Enabling Research Through Quality Reagents
Breakthrough research depends not only on strong ideas and sound experimental design, but also on the quality of the reagents u
Rooted in Organic Chemistry
We are rooted in organic chemistry, with the expertise and practical insight to bring molecular innovations to life through custom synthesis.
Enabling Research Through Quality Reagents
Breakthrough research depends not only on strong ideas and sound experimental design, but also on the quality of the reagents used to test them. We are committed to developing high-quality, reliable compounds that provide a solid foundation for meaningful scientific work.
Our approach emphasizes a deep understanding of each molecule’s properties, stability, and performance over time. We implement rigorous quality control (QC) strategies to ensure consistency, reproducibility, and long-term availability. Purity profiles and specifications are established using a suite of analytical techniques, carefully selected and tailored to each target compound.
Collaborations
Chemistry at the Core
Collaborations
Interested in a Penn MRI research project, or have a proposal you’d like to explore? We welcome collaboration and invite you to start the conversation. We are continually developing new projects and look forward to connecting.